Alexander Stephany

ESR 2: Binders for targeting proteins, small molecules and antibodies

It is exciting to use state-of-the-art techniques to help develop continuous biosensors alongside the other researchers of the CONSENSE ITN.

Host

Supervisor

Olga Kheronsky

Prof Maarten Merkx

The Merkx lab develops biomolecular sensors and actuators for applications in intracellular imaging, point-of-care diagnostics, and antibody based therapies. The project’s aim is to develop reversible peptide and protein binders for continuous sensing. For this, I will be using a combination of protein design and yeast surface display.
I grew up mainly in Belgium, where I did most of my education. As I was always curious about science, I chose to study Biology. Throughout my bachelor I became more passionate about the living world, how biological systems function and can be used in real world applications.
I got my education in Belgium, including my higher education at the Université Catholique de Louvain. I graduated with a bachelor’s in biology (2020) and a master’s degree in Biochemistry and Molecular and Cell Biology (2021). For my master thesis, at the Biochemistry and Genetics of Microorganisms group of my university, I studied L,D transpeptidases (cell wall enzymes) from E.coli. After graduation, I worked as a research assistant in the biochemistry and biophysics team of a small university start-up, developing anti-cancer therapeutics.